RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-101a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; immunohistochemistry etc.
Target
FBJ
Pathway
NA
PubMed ID
Title
MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor- 1 Pathway
Year
2012
Function
Overexpression of miR-101a can mitigate interstitial fibrosis and the deterioration of cardiac performance in postinfarct rats through targeting at c-FOS expression and inhibiting the TGF-beta siganaling pathway.